Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC5L All Species: 22.42
Human Site: Y511 Identified Species: 41.11
UniProt: Q99459 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99459 NP_001244.1 802 92251 Y511 E R E I D D T Y I E D A A D V
Chimpanzee Pan troglodytes XP_518512 698 80173 F452 L P A P K N D F E I V L P E N
Rhesus Macaque Macaca mulatta XP_001100220 802 92232 Y511 E R E V D D T Y I E D A A D V
Dog Lupus familis XP_532156 908 104015 Y617 D R E I D D T Y I E D A A D V
Cat Felis silvestris
Mouse Mus musculus Q6A068 802 92171 Y511 E R E I D D T Y I E D A A D V
Rat Rattus norvegicus O08837 802 92199 Y511 E R E M D D T Y I E D A A D V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511089 803 92142 Y511 D H E V D D T Y V E D A A D V
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957378 800 91707 F511 E T E V D E S F V E D A A E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624906 781 89377 R520 Q Q E L I E Q R K K E L S R R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178584 701 79489 A458 L N I N P E E A L M E Y D N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92948 844 95748 I509 S E E P E E K I E E D M S D R
Baker's Yeast Sacchar. cerevisiae Q03654 590 67712 Q357 S N I K S G K Q L K S R I R K
Red Bread Mold Neurospora crassa Q7SAF6 779 87489 L501 E T E W E L E L P D D Q Q E P
Conservation
Percent
Protein Identity: 100 86.4 99.7 87.4 N.A. 98 97.8 N.A. 93.9 N.A. N.A. 84 N.A. N.A. 63.9 N.A. 58.2
Protein Similarity: 100 86.6 100 88.2 N.A. 99.1 99.2 N.A. 97.6 N.A. N.A. 92.3 N.A. N.A. 77 N.A. 70.2
P-Site Identity: 100 0 93.3 93.3 N.A. 100 93.3 N.A. 73.3 N.A. N.A. 46.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 93.3 N.A. N.A. 93.3 N.A. N.A. 53.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 44.6 31.4 44.3
Protein Similarity: N.A. N.A. N.A. 63 46.6 60.7
P-Site Identity: N.A. N.A. N.A. 26.6 0 20
P-Site Similarity: N.A. N.A. N.A. 46.6 13.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 8 0 0 0 54 54 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 0 54 47 8 0 0 8 70 0 8 54 0 % D
% Glu: 47 8 77 0 16 31 16 0 16 62 16 0 0 24 0 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 16 24 8 0 0 8 39 8 0 0 8 0 16 % I
% Lys: 0 0 0 8 8 0 16 0 8 16 0 0 0 0 8 % K
% Leu: 16 0 0 8 0 8 0 8 16 0 0 16 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 8 0 8 0 0 0 % M
% Asn: 0 16 0 8 0 8 0 0 0 0 0 0 0 8 8 % N
% Pro: 0 8 0 16 8 0 0 0 8 0 0 0 8 0 8 % P
% Gln: 8 8 0 0 0 0 8 8 0 0 0 8 8 0 0 % Q
% Arg: 0 39 0 0 0 0 0 8 0 0 0 8 0 16 16 % R
% Ser: 16 0 0 0 8 0 8 0 0 0 8 0 16 0 0 % S
% Thr: 0 16 0 0 0 0 47 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 24 0 0 0 0 16 0 8 0 0 0 47 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 47 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _